Thalidomide-O-amido-PEG2-NH2.TFA

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Category:Biomedicine   MOQ:100KG  Shipped directly from China

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Introduction

CAS NO.: 1957235-75-4

Product purity: ≥95%

Molecular formula: c23h27f3n4o10

Molecular weight: 576.48

Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

Basic Information

Item Description
Full Name Thalidomide-O-amido-PEG2-NH2.TFA
CAS Number 1957235-75-4
Molecular Formula C23H27F3N4O10
Molecular Weight 576.48
Purity ≥95%
Appearance White to off-white solid or powder
Solubility Soluble in water, DMSO, DMF, DCM
Storage Conditions -20°C for powder, -80°C for solutions

Detailed Information

Item Description
Structure Contains a Thalidomide core linked to a PEG chain with two ethylene oxide units, terminated with an amide group and an amino group in the form of trifluoroacetate (TFA) salt
Reactivity The amino group can react with carboxyl groups to form amide bonds or with aldehydes to form Schiff bases
Applications – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers.
Advantages – Combines the properties of Thalidomide, PEG, and a reactive amino group.<br>- High biocompatibility and versatility in bioconjugation.

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