SH-PEG-SH CAS NO.: 68865-60-1
Biomedicine 2025-03-04
CAS NO.: 68865-60-1
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
SH-PEG-SH: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | SH-PEG-SH (Thiol-PEG-Thiol) |
| CAS Number | 68865-60-1 |
| Molecular Formula | HSCH₂CH₂(OCH₂CH₂)ₙCH₂CH₂SH (where n varies based on PEG chain length) |
| Molecular Weight | Common molecular weights: 0.4k, 0.6k, 1k, 2k, 3.4k, 5k, 10k, 20k |
| Appearance | White to off-white solid or viscous liquid |
| Solubility | Soluble in water, DMSO, DMF, and other organic solvents |
| Storage Conditions | Store at -20°C, keep dry and avoid light |
| Purity | ≥95% |
SH-PEG-SH: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | Thiol-PEG-Thiol, PEG (Thiol)₂, Poly(ethylene glycol) dithiol |
| Applications | – Bioconjugation: Used to link biomolecules for imaging and drug delivery.<br>- Nanotechnology: Used in the functionalization of nanoparticles for biomedical applications.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – Thiol Group: Reacts with maleimide, iodoacetamide, pyridyl disulfide, and other thiol-reactive groups.<br>- PEG Chain: Provides hydrophilicity and reduces protein adsorption. |
| Packaging and Price | – Available in various molecular weights and packaging sizes.<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use |
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