Thalidomide-O-amido-PEG1-NH2.HCl

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Category:Biomedicine

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Introduction

CAS NO.: 2204226-02-6

Product purity: ≥95%

Molecular formula: C19H23ClN4O7

Molecular weight: 454.86

Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

Basic Information

Item Description
Full Name Thalidomide-O-amido-PEG1-NH2.HCl
CAS Number 2204226-02-6
Molecular Formula C19H23ClN4O7
Molecular Weight 454.86
Purity ≥95%
Appearance White to off-white solid or powder
Solubility Soluble in water, DMSO, DMF, DCM
Storage Conditions -5°C, dry, protected from light

Detailed Information

Item Description
Structure Contains a Thalidomide core linked to a PEG chain with one ethylene oxide unit, terminated with an amide group and an amino group in the form of hydrochloride salt
Reactivity The amino group can react with carboxyl groups to form amide bonds or with aldehydes to form Schiff bases
Applications – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers.
Advantages – Combines the properties of Thalidomide, PEG, and a reactive amino group.<br>- High biocompatibility and versatility in bioconjugation.

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