Mal-PEG-Mal
Biomedicine 2025-03-04
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Mal-PEG-Mal: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | Mal-PEG-Mal (Maleimide-PEG-Maleimide) |
| CAS Number | 1207751-12-9 |
| Molecular Formula | (C₄H₂O₂)-PEG-(C₄H₂O₂) (PEG chain length varies) |
| Molecular Weight | Common molecular weights: 2 kDa to 20 kDa |
| Appearance | White to off-white powder |
| Solubility | Soluble in water, DMSO, and other polar solvents |
| Storage Conditions | Store at -5°C, keep dry and avoid light |
| Purity | ≥95% |
Mal-PEG-Mal: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | PEG Dimaleimide, PEG Bismaleimide |
| Applications | – Bioconjugation: Used to link biomolecules for imaging and drug delivery.<br>- Drug Delivery: Enhances solubility and stability of therapeutic agents.<br>- Nanotechnology: Used in the functionalization of nanoparticles for biomedical applications.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – Maleimide Group: Reacts with thiol groups via Michael addition to form stable thioether bonds (pH 6.5-7.5, reaction rate constant ~100 M⁻¹s⁻¹).<br>- PEG Chain: Provides hydrophilicity and reduces protein adsorption. |
| Packaging and Price | – Available in various molecular weights and packaging sizes.<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use |
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