Pomalidomide-PEG6-butyl iodide
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Category：Biomedicine MOQ:100KG Shipped directly from China
Introduction
CAS NO.: 1835705-74-2
Product purity: ≥95%
Molecular formula: C31H44In3O11
Molecular weight: 761.6
Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information
| Item | Description |
|---|---|
| Full Name | Pomalidomide-PEG6-butyl iodide |
| CAS Number | 1835705-74-2 |
| Molecular Formula | C31H44IN3O11 |
| Molecular Weight | 761.60 |
| Purity | ≥95% |
| Appearance | White to off-white solid or powder |
| Solubility | Soluble in DMSO (100 mg/mL, ultrasonic required) |
| Storage Conditions | 2-8°C, dry, protected from light |
Detailed Information
| Item | Description |
|---|---|
| Structure | Contains a Pomalidomide-based cereblon ligand, a PEG chain with six ethylene oxide units, and a terminal butyl iodide group |
| Reactivity | The butyl iodide group is highly reactive with nucleophilic groups such as amines and thiols, making it suitable for bioconjugation applications |
| Applications | – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers. |
| Advantages | – Combines the properties of Pomalidomide, PEG, and a reactive butyl iodide group.<br>- High biocompatibility and versatility in bioconjugation. |
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