Mal-PEG-SCM
Biomedicine 2025-03-04
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information of Mal-PEG-SCM
| Item | Description |
|---|---|
| Full Name | Maleimide-PEG-Succinimidyl Carboxymethyl Ester |
| CAS Number | Not specified |
| Molecular Weight | Commonly available: 1k, 2k, 3.4k, 5k, 10k, 20k |
| Purity | ≥95% |
| Appearance | Solid or viscous liquid, depending on molecular weight |
| Solubility | Soluble in water, DMF, DMSO, DCM |
| Storage Conditions | -20°C, dry, protected from light |
Detailed Information of Mal-PEG-SCM
| Item | Description |
|---|---|
| Structure | Contains a maleimide group at one end and a succinimidyl carboxymethyl ester (SCM) group at the other end of a PEG chain |
| Reactivity | The maleimide group reacts with thiol groups to form stable C-S bonds (optimal pH 6.5-7.5). The SCM group reacts with primary amines to form amide bonds |
| Applications | Used as a cross-linking agent in bioconjugation, drug delivery, and antibody-drug conjugates (ADCs). It is also used in the development of PEGylated hydrogels and other biomaterials |
| Advantages | Provides water solubility, biocompatibility, and flexibility. It enhances stability and reduces immunogenicity of modified molecules |
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