mPEG-SH CAS NO.: 401916-61-8
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Category：Biomedicine Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS NO.: 401916-61-8
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
mPEG-SH: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | mPEG-SH (Methoxy Polyethylene Glycol-Thiol) |
| CAS Number | 401916-61-8 |
| Molecular Formula | HSCH₂CH₂(OCH₂CH₂)ₙOCH₃ (where n varies based on PEG chain length) |
| Molecular Weight | Common molecular weights: 1k, 2k, 3.4k, 5k, 10k, 20k (customizable) |
| Appearance | Solid or liquid, depending on molecular weight |
| Solubility | Soluble in water and most organic solvents (e.g., DMSO, DMF, ethanol) |
| Storage Conditions | Store at -20°C, keep dry and avoid light |
| Purity | ≥95% |
mPEG-SH: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | Methoxy PEG Thiol, mPEG-Thiol, MPEG-SH |
| Structure | – PEG Chain: Provides hydrophilicity and biocompatibility.<br>- Thiol Group: Reactive group that can form covalent bonds with other molecules. |
| Applications | – Bioconjugation: Used to modify proteins, peptides, and other biomolecules by forming stable thioether bonds with thiol-reactive groups.<br>- Drug Delivery: Enhances solubility and stability of therapeutic agents.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – Thiol Group: Reacts with maleimide, iodoacetamide, pyridyl disulfide, and other thiol-reactive groups.<br>- PEG Chain: Provides hydrophilicity and reduces protein adsorption. |
| Packaging and Price | – Available in various molecular weights and packaging sizes (e.g., 100mg, 250mg, 500mg, 1g, 5g).<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use. |
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