COOH-PEG-COOH CAS NO.: 39927-08-7
Biomedicine 2025-03-04
CAS NO.: 39927-08-7
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
COOH-PEG-COOH: Basic Information
| Aspect | Details |
|---|---|
| Chemical Name | COOH-PEG-COOH (Carboxylic Acid Polyethylene Glycol-Carboxylic Acid) |
| CAS Number | 39927-08-7 |
| Molecular Formula | HOOC-CH₂-(O-CH₂-CH₂)ₙ-CH₂-COOH (n varies based on PEG chain length) |
| Molecular Weight | Common molecular weights: 400, 600, 1k, 2k, 3.4k, 5k, 6k, 7k, 10k, 20k (customizable) |
| Appearance | Solid or liquid, depending on molecular weight |
| Solubility | Soluble in water and most organic solvents (e.g., DMSO, DMF, DCM, ethanol) |
| Storage Conditions | Store at -20°C, keep dry and avoid light |
| Purity | ≥95% |
COOH-PEG-COOH: Additional Information
| Aspect | Details |
|---|---|
| Synonyms | CM-PEG-CM, Acid-PEG-Acid, HOOC-PEG-COOH |
| Structure | – PEG Chain: Provides hydrophilicity and biocompatibility.<br>- Carboxylic Acid Groups: Reactive groups that can form ester bonds with alcohols and amide bonds with amines. |
| Applications | – Bioconjugation: Used to modify proteins, peptides, and other biomolecules by forming stable amide bonds with primary amines.<br>- Drug Delivery: Enhances solubility and stability of therapeutic agents.<br>- Surface Functionalization: Used to modify surfaces for improved biocompatibility.<br>- Antibody-Drug Conjugates (ADC): Ideal linker for attaching cytotoxic drugs to antibodies. |
| Chemical Reactivity | – Carboxylic Acid Groups: Reacts with amines to form amide bonds and with alcohols to form ester bonds. |
| Packaging and Price | – Available in various packaging sizes (e.g., 100mg, 250mg, 500mg, 1g, 5g).<br>- Custom synthesis available based on specific requirements. |
| Usage | For research use only, not for human use. |
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