mPEG-SC
We are a manufacturer based in China. We specialize in providing high-quality mPEG-SC for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category：Biomedicine MOQ:100KG Shipped directly from China
Introduction
Product purity: ≥95%
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information of mPEG-SC
| Item | Description |
|---|---|
| Full Name | Methoxy Polyethylene Glycol-Succinimidyl Carbonate |
| CAS Number | 92451-01-9 |
| Molecular Weight | Commonly available: 350, 5k, 10k, 20k |
| Purity | ≥95% |
| Appearance | Solid or powder |
| Solubility | Soluble in water, DMSO, DMF, and common organic solvents |
| Storage Conditions | -20°C, dry, protected from light |
Detailed Information of mPEG-SC
| Item | Description |
|---|---|
| Structure | Consists of a methoxy (OCH3) group at one end of the PEG chain and a succinimidyl carbonate (SC) group at the other end. The SC group is highly reactive with primary amines (-NH2) to form stable urethane bonds. |
| Reactivity | The SC group reacts efficiently with primary amines under mild conditions (pH 7-8.5), forming stable covalent bonds. This makes mPEG-SC ideal for bioconjugation applications. |
| Applications | – Bioconjugation: Used to modify proteins, peptides, and nucleic acids to improve stability, solubility, and reduce immunogenicity.<br>- Drug Delivery: Enhances drug stability and circulation time in the body.<br>- Surface Modification: Improves the biocompatibility of nanoparticles and other materials.<br>- Nanoparticles: Used in the formation of nanoparticles for drug delivery and imaging applications.<br>- Biosensors: Used to immobilize biomolecules for high-sensitivity detection. |
| Advantages | High biocompatibility, good water solubility, and versatile reactivity. The urethane bond formed is more stable than ester bonds, making it suitable for long-term applications. |
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