N3-PEG2-COOH CAS NO.: 1312309-63-9
Biomedicine 2025-03-04
CAS NO.: 1312309-63-9
Product purity: ≥95%
Molecular formula: C7H13N3O4
Molecular weight: 203.19
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information of N3-PEG2-COOH
| Item | Description |
|---|---|
| Full Name | Azide-PEG2-COOH |
| CAS Number | 1312309-63-9 |
| Molecular Formula | C7H13N3O4 |
| Molecular Weight | 203.19 |
| Purity | ≥95% |
| Appearance | Solid or powder |
| Solubility | Soluble in water, DMSO, DMF, DCM |
| Storage Conditions | -5°C, dry, protected from light |
Detailed Information of N3-PEG2-COOH
| Item | Description |
|---|---|
| Structure | Consists of an azide group (N3), a PEG chain with two ethylene oxide units, and a terminal carboxyl group (COOH) |
| Reactivity | The azide group can react with alkynes via click chemistry (e.g., CuAAC) or with DBCO without a catalyst to form stable triazole linkages. The carboxyl group can react with amines in the presence of activators (e.g., EDC or HATU) to form amide bonds. |
| Applications | Used in bioconjugation, drug delivery, surface functionalization, and as a building block in polymer chemistry. It is also used in medical research, nanotechnology, cell culture, ligand studies, and as a support for polypeptide synthesis. |
| Advantages | High reactivity, good water solubility, and biocompatibility |
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