Methoxy-polyethylene glycol-maleimide
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Category：Other Pharmaceutical Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS: 724722-89-8
Catalog: HY-W020780
| Aspect | Details |
|---|---|
| Structure | Consists of a methoxy-terminated PEG chain and a maleimide functional group. The PEG chain provides hydrophilicity and biocompatibility, while the maleimide group offers high reactivity. |
| Applications | Widely used in bioconjugation, drug delivery, and surface modification. It can be conjugated to biomolecules like proteins, peptides, and antibodies through thiol-maleimide coupling. |
| Reactivity | The maleimide group readily reacts with thiol (-SH) groups under mild conditions (pH 6.5-7.5), forming stable thioether bonds. |
| Molecular Weight | Available in various molecular weights, commonly ranging from 500 to 20,000 Da, with specific weights like 2k, 3.4k, 5k, and 10k. |
| Storage Conditions | Should be stored at -20°C in a dry, light-protected environment to maintain stability and activity. Avoid frequent freeze-thaw cycles. |
| Purity | Typically has a purity of >95%, ensuring reliable performance in bioconjugation and other applications. |
| Solubility | Soluble in water, chloroform, and DMSO at concentrations up to 10 mg/mL. |
| Stability | Stable for up to 1 year when stored properly at -20°C and kept dry. |
| Customization | Can be customized for specific molecular weights and applications. |
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