distearoyl-rac-glycerol-PEG CAS:308805-39-2
We are a manufacturer based in China, specializing in high-quality distearoyl-rac-glycerol-PEG CAS:308805-39-2 for industrial clients worldwide. Technical support and custom formulation available.
Category：Other Pharmaceutical | Brand：MT
Factory Direct
7-30 Days Lead Time
MOQ: 100KG
Global Export
Introduction
CAS:308805-39-2
Catalog:HY-W591381
| Aspect | Details |
|---|---|
| Structure | DSG-PEG is a two-phasic molecule comprising a hydrophobic distearoyl glycerol (DSG) segment and a hydrophilic polyethylene glycol (PEG) segment. The DSG part consists of two 18-carbon saturated fatty acids (stearic acids) esterified to a glycerol molecule, while the PEG segment provides water solubility and biocompatibility. |
| Molecular Weight | The PEG segment typically has a molecular weight of around 2,000 Da, resulting in an overall molecular weight of approximately 2,621.6 Da. |
| Appearance | White to off-white powder. |
| Solubility | Soluble in methanol, chloroform, and partially soluble in water. |
| Storage | Stored at -20°C with a shelf life of 1 year. |
| Applications | Widely used in liposome and lipid nanoparticle (LNP) formulations for drug delivery, including small molecule drugs, nucleic acids (e.g., mRNA, siRNA), and proteins. It enhances stability, prolongs circulation time, and reduces immunogenicity. |
| Surface Modification | Used to modify the surface of liposomes or nanoparticles to provide a “stealth” effect, reducing clearance by the immune system. |
| Customization | Available in different PEG molecular weights and can be tailored for specific applications. |
| Research Use | For research purposes only, not for human use |
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