Zoledronic acid CAS NO.118072-93-8
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Category：Active Pharmaceutical Ingredients MOQ:100KG Shipped directly from China
Introduction
Catalog ID80016992
CAS NO.118072-93-8
Purity 98%
MDL NumberMFCD00867791
EINEC Molecular Formula C5H10N2O7P2.H2O
Molecular Weight 290.1049
| Aspect | Details |
|---|---|
| Chemical Structure | – Molecular Formula: C₅H₁₀N₂O₆P₂<br>- Molecular Weight: 222.08 |
| Mechanism of Action | – Zoledronic acid is a bisphosphonate that inhibits osteoclastic bone resorption, reducing bone loss and increasing bone density.<br>- It also reduces calcium release into the blood, lowering calcium levels. |
| Clinical Uses | – Treatment and prevention of osteoporosis in postmenopausal women and men.<br>- Treatment of Paget’s disease.<br>- Management of high calcium levels due to cancer.<br>- Treatment of bone problems from multiple myeloma or cancer that has spread to the bone. |
| Dosage Forms | – Injectable solution. |
| Storage Conditions | – Usually administered by healthcare providers in a hospital or clinic. |
| Side Effects | – Common: Flu-like symptoms (fever, chills), headache, bone, muscle, or joint pain.<br>- Serious: Osteonecrosis of the jaw, atypical femur fractures, kidney problems, hypocalcemia.<br>- Other: Nausea, vomiting, diarrhea, constipation. |
| Special Precautions | – Monitor renal function regularly.<br>- Inform doctors of dental history and avoid invasive dental procedures.<br>- Monitor calcium levels, especially in patients with a history of hypocalcemia.<br>- Use with caution in pregnant or breastfeeding women. |
| Research Applications | – Investigated for its effects on bone metabolism and cancer-related bone complications.<br>- Studied for its potential in reducing skeletal-related events in patients with bone metastases |
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