Yohimbine HCl
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80020535
CAS NO.65-19-0
Purity 99%
MDL NumberMFCD00012674
EINEC200-600-4
Molecular FormulaC21H26N2O3.HCl
Molecular Weight390.9037
Melting point: 273~301℃
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₂₁H₂₇ClN₂O₃ <br>- Molecular Weight: 394.91 g/mol <br>- Melting Point: 288-290°C <br>- Appearance: White to slightly yellow powder, slightly fragrant, bitter taste <br>- Solubility: Easily soluble in chloroform, soluble in methanol and ethanol, slightly soluble in water |
| Mechanism of Action | – Acts as an α₂-adrenergic receptor antagonist.<br>- Increases sympathetic outflow by blocking central α₂-adrenergic receptors, leading to increased norepinephrine release.<br>- May also involve other neurotransmitters like dopamine and serotonin. |
| Clinical Uses | – Erectile Dysfunction: Used to treat impotence by increasing sympathetic drive and improving erectile function.<br>- Neurological Disorders: Used in the treatment of certain neurological conditions.<br>- Veterinary Medicine: Reverses the effects of xylazine in animals. |
| Pharmacokinetics | – Rapidly absorbed orally with variable bioavailability (7-87%, mean 33%).<br>- Metabolized extensively in the liver or kidneys.<br>- Elimination half-life is approximately 36 minutes. |
| Adverse Effects | – High blood pressure, increased heart rate, headache, anxiety, dizziness, nausea, vomiting, tremors, and sleeplessness.<br>- Can be dangerous if taken in large doses or for long periods.<br>- Should not be used with MAO inhibitors or in patients with kidney problems. |
| Storage Conditions | Store at room temperature |
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