Active Pharmaceutical Ingredients

Catalog ID80017986

CAS NO.1218-35-5

Purity 98%

MDL NumberMFCD00238707

Molecular FormulaC16H24N2.HCl

Molecular Weight280.8361

Melting point: >300°C

Category	Details
Chemical Properties	Molecular formula: C16H25ClN2<br> Molecular weight: 280.84 g/mol
Physical Properties	Appearance: White to off-white solid<br> Melting point: 131–133°C
Mechanism of Action	Acts as an α-adrenergic receptor agonist, primarily targeting α1A and α2B receptors. It constricts nasal blood vessels, reducing swelling and congestion.
Therapeutic Uses	Nasal Congestion: Used to relieve nasal congestion caused by the common cold, sinusitis, allergic rhinitis, and other respiratory conditions.<br> Research: Investigated for its effects on nasal mucosa and potential use in treating sinusitis.
Formulations	Available as a nasal spray (0.05% concentration) for topical use.
Dosage	Adults and children over 12 years: 1–2 sprays per nostril every 8–10 hours.<br> Children aged 6–12: 1 spray per nostril every 8–10 hours.
Storage Conditions	Store at room temperature, protect from moisture and heat.
Safety Information	Side Effects: Temporary burning, stinging, dryness in the nose, runny nose, and sneezing.<br> Contraindications: Avoid in patients with narrow-angle glaucoma, severe cardiovascular disease, or those taking MAOIs.<br> Pregnancy and Lactation: Use with caution; consult a doctor.<br> Rebound Congestion: Prolonged use (more than 3 days) can lead to worsening of nasal congestion.

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