What Is 2,5-Dibromo-1,3-Dichlorobenzene Uesd For?

FAQ 2025-04-10

2,5-Dibromo-1,3-dichlorobenzene (CAS No. 19393-97-6) is a halogenated aromatic compound with the molecular formula C₆H₂Br₂Cl₂. It is widely used in various industrial and research applications due to its unique chemical properties.

1. Pharmaceutical Intermediate

  • Synthesis of Active Pharmaceutical Ingredients (APIs): 2,5-Dibromo-1,3-dichlorobenzene serves as a key intermediate in the production of pharmaceuticals, particularly in the development of drugs with specific therapeutic properties. Its bromine and chlorine substituents make it suitable for further functionalization, enabling the synthesis of complex molecular structures required for drug efficacy.

2. Agrochemical Synthesis

  • Pesticides and Herbicides: In the agrochemical industry, this compound is utilized to produce pesticides and herbicides. The bromine and chlorine atoms enhance the stability and bioactivity of the resulting compounds, improving their effectiveness in controlling pests and weeds.

3. Material Science and Polymers

  • Monomer for Polymer Synthesis: It can be used as a monomer in the production of specialized polymers and copolymers. The halogenated groups allow for cross-linking and other chemical modifications, leading to materials with unique physical and chemical properties.

4. Dye and Pigment Industry

  • Synthesis of Dyes and Pigments: 2,5-Dibromo-1,3-dichlorobenzene is employed in the synthesis of dyes and pigments, particularly those used in textiles, printing inks, and coatings. The halogenated structure contributes to the colorfastness and stability of the final products.

5. Organic Synthesis and Research

  • Building Block for Organic Synthesis: As a versatile intermediate, it is used in various organic transformations, including nucleophilic aromatic substitution and cross-coupling reactions. These reactions enable the construction of more complex organic molecules with tailored properties.
  • Research Applications: It is also used in academic and industrial research for the development of new materials, catalysts, and functional molecules.

6. Electronic Materials

  • Semiconductor and Conductive Polymers: The compound’s unique electronic properties make it relevant in the development of electronic materials, such as semiconductors and conductive polymers, which are used in electronics and optoelectronics.

7. Chemical Catalysis

  • Catalyst Precursors: In some cases, 2,5-dibromo-1,3-dichlorobenzene can serve as a precursor for the synthesis of catalysts used in various chemical reactions, including oxidation and reduction processes.

Physical and Chemical Properties:

  • Appearance: White to off-white crystalline solid.
  • Melting Point: Approximately 105-107°C.
  • Solubility: Insoluble in water but soluble in organic solvents like ethanol, dichloromethane, and acetone.
  • Stability: Stable under normal conditions but should be handled with care due to its reactivity and potential hazards.

Safety and Handling:

  • Hazards: Classified as irritant and potentially harmful if inhaled, ingested, or in contact with skin or eyes.
  • Handling Precautions: Use appropriate personal protective equipment (PPE), ensure proper ventilation, and store in a cool, dry place away from heat and incompatible materials.