FAQ

2,2′-Azobis(2-methylpropionamidine) dihydrochloride (CAS No. 2997-92-4) is a chemical compound primarily used as a free radical initiator in polymerization reactions and biochemical research.

1. Polymerization Initiator:
   • Serves as an efficient initiator for the polymerization of acrylic, vinyl, and allylic monomers, enabling the synthesis of polymers with controlled molecular weights and structures.
   • Particularly effective in aqueous solutions and emulsions, where its water-soluble nature facilitates uniform polymerization.
2. Biochemical Research:
   • Utilized to generate free radicals in controlled experimental settings, aiding studies on oxidative stress, lipid peroxidation, and DNA damage in biological systems.
   • Helps elucidate mechanisms of cellular damage and antioxidant efficacy.
3. Chemical Synthesis:
   • Acts as an intermediate in the production of pharmaceuticals, dyes, and other specialty chemicals, where precise radical-mediated reactions are required.

Properties:

• Molecular Formula: C₈H₂₀Cl₂N₆
• Molecular Weight: 271.19 g/mol
• Physical State: White to off-white crystalline solid
• Solubility: Soluble in water, acetone, dioxane, methanol, ethanol, DMSO, and other polar solvents
• Stability: Sensitive to heat, light, and strong oxidizing agents; requires storage in cool, dry conditions.

Safety Considerations:

• Toxicity: High toxicity (oral LD₅₀ in rats: 410 mg/kg); may cause skin sensitization and irritation upon contact.
• Handling: Requires appropriate personal protective equipment (PPE) and adherence to safety protocols to minimize exposure risks.