FAQ

2-Chloro-4,5-difluorobenzoic acid (CAS No. 110877-64-0) is primarily utilized as an intermediate in pharmaceutical and agrochemical synthesis. Its key applications include:

1. Pharmaceuticals:
   • Antibacterial Agents: It serves as a crucial building block for synthesizing novel antibacterial drugs, particularly in the fluoropyridone carboxylic acid class, which exhibits broad-spectrum antimicrobial activity.
   • Cardiovascular Medications: The compound is employed in the development of drugs targeting heart and blood vessel disorders, leveraging its fluorinated aromatic structure to enhance potency and selectivity.
2. Agrochemicals:
   • Fungicides and Herbicides: Its fluorinated motif contributes to the design of advanced pesticides, offering improved environmental stability and target specificity.
3. Synthetic Utility:
   • The acid’s carboxylic acid and halogenated aromatic functionalities enable versatile transformations, including amidation, esterification, and coupling reactions, facilitating the construction of complex molecular architectures.

Safety and Handling:

• As a hazardous material, it requires careful storage in cool, dry conditions away from oxidizing agents and strong bases. Appropriate personal protective equipment (PPE) is essential during handling to mitigate risks of skin irritation, eye damage, and inhalation exposure.

This compound’s strategic role in drug discovery and agrochemical innovation underscores its significance in modern chemical synthesis.