Voriconazole
We are a manufacturer based in China. We specialize in providing high-quality Voriconazole for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80071719
CAS NO.137234-62-9
Purity 98%
MDL NumberMFCD00905717
Molecular Formula C16H14N5OF3
Molecular Weight 349.3105
Melting point: 127~130°C
| Item | Information |
|---|---|
| Mechanism of Action | Voriconazole is a broad-spectrum antifungal agent that inhibits the synthesis of ergosterol, a key component of fungal cell membranes, thereby disrupting fungal cell integrity and growth. |
| Indications | Voriconazole is used to treat serious fungal infections, including invasive aspergillosis, candidemia, esophageal candidiasis, and other severe fungal infections caused by susceptible species. |
| Dosage Forms | Available as tablets (50 mg, 200 mg), oral suspension (40 mg/mL), and injection. |
| Storage Conditions | Tablets and oral suspension should be stored at room temperature (68-77°F or 20-25°C) and protected from light. The injection form is usually administered in a hospital or clinic. |
| Common Side Effects | Rash, headache, nausea, vomiting, diarrhea, visual disturbances (e.g., blurred vision, color changes), photosensitivity, and liver function abnormalities. |
| Serious Side Effects | Severe skin reactions (e.g., Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis), kidney damage, adrenal gland problems, bone pain, and pancreatitis. |
| Drug Interactions | Voriconazole interacts with many medications, including corticosteroids, QT-prolonging drugs, sirolimus, rifampin, carbamazepine, phenytoin, ritonavir, and St. John’s wort. |
| Special Precautions | Avoid direct sunlight and use sunscreen due to photosensitivity. Regular liver function monitoring is recommended. Patients should avoid alcohol and high-fat foods. |
| Pregnancy and Lactation | Voriconazole can harm the unborn baby and is not recommended during pregnancy or breastfeeding |
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