Vitamin B12 (Mecobalamin) CAS 13422-55-4
Vitamins 2025-03-11
Mecobalamin is a derivative of vitamin B12. Compared with vitamin B12, Mecobalamin can improve the conduction of neurons. Its methylated functional groups can participate in the activity of methyl transfer in the biochemical process of the body, promote the metabolism of nucleic acid, protein and fat in nerve tissue, stimulate the synthesis of lecithin in Schwann cells, repair the damaged myelin sheath, and improve the nerve conduction velocity.
Product name:Vitamin B12 (Mecobalamin)
Molecular Formula:C63H91CoN13O14P
Molecular Weight:1344.382
CAS No.:13422-55-4
Description
Vitamin B12 (Mecobalamin) occurs as dark red crystals or crystalline powder. It is sparingly soluble in water, slightly soluble in ethanol (99.5), and practically insoluble in acetonitrile. It is affected by light.
Application
Vitamin B12 (Mecobalamin) is used to treat megaloblastic anemia caused by vitamin B12 deficiency and also for peripheral neuropathy.
Specification
| Category | Parameters |
|---|---|
| Chemical Identity | |
| – IUPAC Name | Mecobalamin (5′-deoxyadenosylcobalamin). |
| – CAS Number | 13422-55-4. |
| – Molecular Formula | C₆₃H₈₈CoN₁₄O₁₄P. |
| – Molecular Weight | 1355.38 g/mol. |
| Physical Properties | |
| – Appearance | Dark red crystalline powder. |
| – Solubility | Slightly soluble in water; insoluble in ethanol. |
| – Melting Point | ~220°C (dec.). |
| Quality Standards | |
| – Assay (USP/EP) | ≥97% (as mecobalamin). |
| – Loss on Drying | ≤3.0%. |
| – Residue on Ignition | ≤0.2%. |
| – Heavy Metals | ≤10 ppm. |
| – Cobalt Content | 4.1–4.4% (w/w). |
| Applications | |
| – Pharmaceuticals | Treatments for anemia, neuropathy, cognitive decline. |
| – Dietary Supplements | Sublingual tablets, oral sprays. |
| – Food Fortification | Plant-based meat alternatives, nutritional yeast. |
| Storage | Cool (<25°C), dry, airtight container; protect from light. Shelf life: 24 months. |
| Regulatory Status | GRAS (FDA); USP/NF, EP, JP monographs. |
