Vitamin B12 (Cyanocobalamin) CAS 68-19-9
Vitamins 2025-03-11
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Molecular Formula
C63H88CoN14O14P
Molecular Weight
1355.38
CAS No.
68-19-9
Description
Vitamin B12 occurs as dark red crystals or as an amorphous or crystalline powder. In the anhydrous form, it is very hygroscopic, and when exposed to air, it may absorb about 12% of water. It is sparingly soluble in water; soluble in alcohol; and insoluble in acetone, in chloroform, and in ether.
Application
In medical and health care, Vitamin B12is mainly used to treat various VB12 deficiency diseases, such as megaloblastic anemia, anemia caused by drug poisoning, aplastic anemia and leukopenia. In feed additives, VB12 can promote the growth and development of poultry, livestock, especially young birds and young animals, and improve the utilization of feed protein.
Specification
| Category | Parameters |
|---|---|
| Chemical Identity | |
| – IUPAC Name | Cyanocobalamin (5′-deoxyadenosylcobalamin). |
| – CAS Number | 68-19-9. |
| – Molecular Formula | C₆₃H₈₈CoN₁₄O₁₄P. |
| – Molecular Weight | 1355.38 g/mol. |
| Physical Properties | |
| – Appearance | Dark red crystalline powder. |
| – Solubility | Slightly soluble in water; insoluble in ethanol. |
| – Melting Point | ~200°C (dec.). |
| Quality Standards | |
| – Assay (USP/EP) | ≥98% (as cyanocobalamin). |
| – Loss on Drying | ≤3.0%. |
| – Residue on Ignition | ≤0.2%. |
| – Heavy Metals | ≤10 ppm. |
| – Cyanide Content | ≤0.1% (w/w). |
| – Cobalt Content | 4.1–4.4% (w/w). |
| Applications | |
| – Pharmaceuticals | Injections for vitamin B12 deficiency, anemia. |
| – Dietary Supplements | Tablets, capsules, sublingual forms. |
| – Food Fortification | Breakfast cereals, plant-based beverages. |
| Storage | Cool (<25°C), dry, airtight container; protect from light. Shelf life: 24 months. |
| Regulatory Status | GRAS (FDA); USP/NF, EP, JP monographs. |
