Ursolic acid CAS NO.77-52-1
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80017034
CAS NO.77-52-1
Purity 98%
MDL NumberMFCD00009621
EINEC201-034-0
Molecular Formula C30H48O3
Molecular Weight 456.7003
| Aspect | Details |
|---|---|
| Definition | Ursolic acid is a naturally occurring pentacyclic triterpenoid compound found in various plants, particularly in apple peels, rosemary, and other herbs. |
| Chemical Structure | – Molecular formula: C₃₀H₄₈O₃<br>- Molecular weight: 456.7 g/mol.<br>- Consists of five interconnected carbon rings with a hydroxyl group at C-3 and a carboxylic acid group at C-17. |
| Mechanism of Action | – Exhibits anti-inflammatory, antioxidant, antimicrobial, anticancer, hepatoprotective, and metabolic-regulating properties.<br>- Inhibits various pathways involved in cancer cell proliferation, inflammation, and oxidative stress.<br>- Enhances muscle growth and exercise capacity by promoting protein synthesis and reducing muscle breakdown. |
| Clinical Uses | – Potential applications in treating cancer, neurological disorders, metabolic diseases, and cardiovascular conditions.<br>- Used in traditional medicine for its health-promoting properties.<br>- Investigated for its role in preventing obesity, diabetes, and improving liver health. |
| Natural Sources | Found in apple peels, rosemary, thyme, oregano, lavender, coffee, and various medicinal herbs. |
| Pharmacokinetics | – Metabolized in the liver through phase I and II processes, excreted via bile or urine.<br>- Poor solubility in water, which can limit its bioavailability. |
| Side Effects | Generally considered safe, but may interact with medications metabolized by liver enzymes. |
| Research Applications | – Studied for its potential as an anti-cancer agent, with clinical trials suggesting its practical use.<br>- Investigated for its effects on muscle health, exercise performance, and various chronic illnesses |
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