Urapidil CAS NO.34661-75-1
We are a manufacturer based in China. We specialize in providing high-quality Urapidil CAS NO.34661-75-1 for industrial clients across various sectors. Whether you need chemicals consultation or technical support, our team is here to help.
Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017865
CAS NO.34661-75-1
Purity 96%
MDL NumberMFCD00133908
Molecular Formula C20H29N5O3
Molecular Weight 387.476
Melting point: 156~158°C
| Category | Details |
|---|---|
| Chemical Properties | Molecular formula: C20H29N5O3<br> Molecular weight: 387.48 g/mol |
| Mechanism of Action | Urapidil is a selective α1-adrenoceptor antagonist with a dual mechanism of action. It lowers blood pressure by blocking peripheral α1-adrenoceptors, leading to vasodilation. Additionally, it acts centrally by stimulating serotonin 5-HT1A receptors, reducing sympathetic activity. |
| Therapeutic Uses | Hypertension: Used for treating hypertension, including hypertensive crises, perioperative hypertension, and pre-eclampsia.<br> Acute Heart Failure: Effective in elderly hypertensive patients with acute heart failure. |
| Pharmacokinetics | Absorption: Well-absorbed orally, with peak plasma concentrations reached within 0.5–1 hour.<br> Distribution: Plasma protein binding rate is about 80%.<br> Metabolism: Metabolized primarily in the liver.<br> Excretion: 50%–70% excreted in urine, with a terminal half-life of 2.7 hours. |
| Formulations | Available as tablets and intravenous injections. |
| Storage Conditions | Store at room temperature, protected from light and moisture. |
| Safety Information | Side Effects: Dizziness, nausea, headache, fatigue, palpitations.<br> Contraindications: Not recommended for patients with aortic stenosis or arteriovenous shunts.<br> Special Populations: Use with caution in elderly patients due to prolonged elimination half-life. |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.
Inquiry
Factory & Shipment
