Agrochemicals

Trifluoroacetyl Chloride 

CAS No.: 354-32-5 | EC No.: 206-556-2 | UN No.: 3057

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1. Chemical Identification

Property	Specification
IUPAC Name	2,2,2-Trifluoroacetyl chloride
Molecular Formula	C₂ClF₃O
Molecular Weight	132.47 g/mol
Appearance	Colorless gas
Density	1.335 g/cm³ (liquid at 20°C)
Melting Point	-146°C
Boiling Point	-27°C
Refractive Index	1.309
Flash Point	-58.1±25.9°C

Synonyms:
TFAC, Perfluoroacetyl chloride

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2. Key Applications

Agrochemical Synthesis

• Fluorinated Pesticides: Key intermediate for modern crop protection agents

Pharmaceutical Manufacturing

• Active Ingredients: Production of fluorinated drugs
• Peptide Synthesis: Protecting group reagent

Specialty Chemicals

• Fluorinated organic intermediates
• Fine chemical production

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3. Product Advantages

✔ High Reactivity – Excellent acylating agent
✔ Fluorine Synergy – Enhances bioactivity of end products
✔ Process Efficiency – Enables clean reaction pathways

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4. Physical & Chemical Properties

• Solubility:
  • Reacts violently with water/alcohols
  • Soluble in inert organic solvents
• Stability:
  • Moisture-sensitive – store under dry inert gas
  • Corrosive to most metals

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5. Handling & Storage

Parameter	Requirement
Storage Temp	-20°C (cylinder)
Packaging	10kg stainless steel cylinders
Special Notes	Use nickel/alloy equipment

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6. Safety Information

Danger!

• H314: Causes severe skin burns and eye damage
• H330: Fatal if inhaled
• H331: Toxic if inhaled

Protective Measures:

• P260: Do not breathe gas
• P280: Wear face shield/acid-resistant gloves
• P310: Immediate medical attention required

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7. Quality Specifications

• Purity: ≥99% (GC)
• Acid Content: ≤0.1%
• Non-volatile Matter: ≤0.01%

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