Triamterene CAS: 396-01-0

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Introduction

CAS: 396-01-0

Appearance: Yellow solid

Purity: ≥99% Capacity: 200mt/year MOQ: 182g

Application: Organic Intermediate

Standard: Enterprise export

Manufacturer: Jinan Finer Chemical Co., Ltd

Synonyms: 2,4,7-Triamino-6-phenylpteridine 6-Phenyl-2,4,7-pteridinetriamine

Molecular Formula: C12H11N7

Molecular Weight: 253.26

CAS Registry Number: 396-01-0

EINECS: 206-904-3

Melting point: 316 ºC

Water solubility: <0.1 g/100 mL at 20 ºC

Triamterene (CAS: 396-01-0), also known as 2,4,7-Triamino-6-phenylpteridine, is a weak diuretic medication. It acts primarily by inhibiting the exchange of sodium and potassium ions in the distal tubule and collecting duct of the kidney, resulting in increased excretion of sodium, chloride, and water while decreasing potassium loss. This medication is used to treat conditions such as low blood potassium levels, hyperchloremic acidosis, and various causes of refractory edema, including heart failure, liver cirrhosis, and chronic nephritis.

Property Category Details
Chemical Name Triamterene
CAS Number 396-01-0
Physical Properties
– Melting Point 316°C
– Boiling Point 573.4°C at 760 mmHg (rough estimate: 386.46°C)
– Density 1.502 g/cm3 (rough estimate: 1.3215 g/cm3)
– Appearance Yellow crystalline powder
– Solubility <0.1 g/100 mL in water at 20°C
Chemical Properties
– Molecular Formula C12H11N7
– Molecular Weight 253.26 g/mol
– Refractive Index 1.8260 (estimate)
– Flash Point 11°C
– pH (pKa) 6.2 at 25°C

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