Triamterene CAS: 396-01-0
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Category：Chemical Intermediates MOQ:100KG Shipped directly from China
Introduction
CAS: 396-01-0
Appearance: Yellow solid
Purity: ≥99% Capacity: 200mt/year MOQ: 182g
Application: Organic Intermediate
Standard: Enterprise export
Manufacturer: Jinan Finer Chemical Co., Ltd
Synonyms: 2,4,7-Triamino-6-phenylpteridine 6-Phenyl-2,4,7-pteridinetriamine
Molecular Formula: C12H11N7
Molecular Weight: 253.26
CAS Registry Number: 396-01-0
EINECS: 206-904-3
Melting point: 316 ºC
Water solubility: <0.1 g/100 mL at 20 ºC
Triamterene (CAS: 396-01-0), also known as 2,4,7-Triamino-6-phenylpteridine, is a weak diuretic medication. It acts primarily by inhibiting the exchange of sodium and potassium ions in the distal tubule and collecting duct of the kidney, resulting in increased excretion of sodium, chloride, and water while decreasing potassium loss. This medication is used to treat conditions such as low blood potassium levels, hyperchloremic acidosis, and various causes of refractory edema, including heart failure, liver cirrhosis, and chronic nephritis.
| Property Category | Details |
|---|---|
| Chemical Name | Triamterene |
| CAS Number | 396-01-0 |
| Physical Properties | |
| – Melting Point | 316°C |
| – Boiling Point | 573.4°C at 760 mmHg (rough estimate: 386.46°C) |
| – Density | 1.502 g/cm3 (rough estimate: 1.3215 g/cm3) |
| – Appearance | Yellow crystalline powder |
| – Solubility | <0.1 g/100 mL in water at 20°C |
| Chemical Properties | |
| – Molecular Formula | C12H11N7 |
| – Molecular Weight | 253.26 g/mol |
| – Refractive Index | 1.8260 (estimate) |
| – Flash Point | 11°C |
| – pH (pKa) | 6.2 at 25°C |
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