trans-3,5-Difluorocinnamic acid
Pharmaceutical Materials 2025-03-20
CAS.No：147700-58-1
Appearance:White powder
Molecular Formula:C9H6F2O2
Purity:HPLC≥99.5%
Molecular weight:184.14
Capacity:20 tons/month
Application:Pharmaceutical intermediates
| Property | Details |
|---|---|
| Molecular Formula | C9H7F2O2 |
| Molecular Weight | 185.15 g/mol |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥97% |
| Melting Point | 198-202 °C |
| Boiling Point | Predicted to be above 300 °C at 760 mmHg |
| Density | Approximately 1.3 g/cm³ (Predicted) |
| Solubility | Soluble in organic solvents such as ethanol, DMSO, and methanol; slightly soluble in water |
| Applications | Organic synthesis, pharmaceuticals, materials science, and biochemical research |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from moisture and strong acids |
| Suppliers | Available from specialized chemical suppliers |
Applications
trans-3.5-Difluorocinnamic acid is a versatile compound widely used in organic synthesis. Its difluorinated cinnamic acid structure provides unique reactivity, making it a valuable intermediate in the synthesis of various fluorinated compounds. In pharmaceuticals, this compound is utilized in the development of drugs with enhanced metabolic stability and bioavailability, contributing to the creation of new therapeutic agents.
In materials science, trans-3.5-Difluorocinnamic acid serves as a building block for the synthesis of polymers and functional materials with tailored properties. Its fluorinated nature can modulate the physical and chemical properties of materials, leading to improved performance in various applications.
Additionally, this compound finds applications in biochemical research, where it is used to explore new chemical entities and biological pathways. Its solubility in organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
