Thiamine Hydrochloride
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Category：Vitamins Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Molecular Formula: C12H17ClN4OS,HCL
Molecular Weight: 337.3
CAS No.: 67-03-8
Product name:Thiamine Hydrochloride (Vitamin B1)
Description
Thiamine Hydrochloride occurs as a white or almost white, crystalline powder or colourless crystals. When exposed to air, the anhydrous product rapidly absorbs about 4% of water. It melts at about 248° with some decomposition. One gram dissolves in about 1 mL of water and in about 100 mL of alcohol. It is soluble in glycerin, and is insoluble in ether.
Application
Thiamine hydrochloride is mainly used for the prevention and treatment of vitamin B1 deficiency and beriberi caused by it. It is also used for adjuvant treatment of peripheral neuritis, myocarditis, dyspepsia and congestive heart failure.
Specification
| Category | Parameters |
|---|---|
| Chemical Identity | |
| – IUPAC Name | Thiamine hydrochloride. |
| – CAS Number | 67-03-8. |
| – Molecular Formula | C₁₂H₁₅ClN₄OS·HCl. |
| – Molecular Weight | 337.25 g/mol. |
| Physical Properties | |
| – Appearance | White to off-white crystalline powder. |
| – Solubility | Freely soluble in water; slightly soluble in ethanol. |
| – pH (1% solution) | 2.5–4.5. |
| Quality Standards | |
| – Assay (USP/EP) | ≥99% (dried basis). |
| – Loss on Drying | ≤2%. |
| – Heavy Metals | ≤10 ppm. |
| – Residual Solvents | Meets ICH Q3C guidelines. |
| Applications | |
| – Food Fortification | Beverages, cereals, infant formulas. |
| – Pharmaceuticals | Multivitamin formulations; neuropathy treatments. |
| – Feed Additives | Livestock nutrition; aquatic feed. |
| Storage | Cool (<25°C), dry, airtight container; protect from light. Shelf life: 36 months. |
| Regulatory Status | GRAS (FDA); USP/NF, EP, JP monographs. |
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