News

4-Bromo-2-fluorobenzonitrile (CAS No. 105942-08-3) is widely utilized in the chemical industry as a versatile intermediate for synthesizing complex organic compounds, pharmaceuticals, pesticides, and advanced materials. 

1. Pharmaceutical Intermediate:
   • Serves as a crucial building block for the synthesis of antiviral drugs, anticancer agents, and antidepressants. Its structure allows for the introduction of functional groups essential for bioactivity, making it valuable in drug discovery and development.
   • Utilized in the preparation of heterocyclic compounds and fluorinated molecules, which are prevalent in modern pharmaceuticals due to fluorine’s ability to enhance metabolic stability and binding affinity to biological targets.
2. Pesticide and Agrochemical Synthesis:
   • Acts as an intermediate in the production of herbicides, fungicides, and insecticides. The fluorine atom and nitrile group contribute to the compound’s efficacy and environmental stability.
3. Liquid Crystal and Display Materials:
   • Employed in the synthesis of liquid crystal compounds used in LCD displays and optical devices. Its structural properties enable the formation of mesophases critical for liquid crystal functionality.
4. Organic Synthesis and Catalysis:
   • Functions as a key intermediate in the preparation of fluorinated organic compounds, which are essential in the synthesis of functional materials, dyes, and pigments.
   • Utilized in cross-coupling reactions (e.g., Suzuki coupling) to form carbon-carbon bonds, facilitating the construction of complex molecular architectures.
5. Advanced Materials:
   • Contributes to the development of fluorinated polymers, electronic materials, and specialty chemicals with enhanced properties such as heat resistance, chemical stability, and optical clarity.
6. Chemical Research and Development:
   • Acts as a probe or reagent in organic chemistry research to study reaction mechanisms and develop new synthetic methodologies.

Properties and Handling:

• Physical Form: White to light brown crystalline powder.
• Solubility: Insoluble in water but soluble in organic solvents like N,N-dimethylformamide (DMF), dichloromethane, and ethyl acetate.
• Safety: Requires careful handling due to potential hazards associated with inhalation, ingestion, or skin contact.