Thalidomide-O-PEG4-t-butyl ester
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Category：Biomedicine Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
CAS NO.: 2411681-87-1
Product purity: ≥95%
Molecular formula: C28H38N2O11
Molecular weight: 578.61
Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information
| Item | Description |
|---|---|
| Full Name | Thalidomide-O-PEG4-t-butyl ester |
| CAS Number | 2411681-87-1 |
| Molecular Formula | C28H38N2O11 |
| Molecular Weight | 578.6 |
| Purity | ≥95% to ≥98% |
| Appearance | White to off-white solid or powder |
| Solubility | Soluble in DMSO, DMF, DCM, and water |
| Storage Conditions | -20°C, dry, protected from light |
Detailed Information
| Item | Description |
|---|---|
| Structure | Consists of a Thalidomide core, a PEG chain with four ethylene oxide units, and a t-butyl ester group |
| Reactivity | The t-butyl ester group can be hydrolyzed to form a carboxylic acid, making it suitable for further conjugation with amines or other nucleophiles |
| Applications | – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers. |
| Advantages | – Combines the properties of Thalidomide, PEG, and a reactive t-butyl ester group.<br>- High biocompatibility and versatility in bioconjugation. |
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