Thalidomide-O-PEG4-t-butyl ester

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Category:Biomedicine   MOQ:100KG  Shipped directly from China

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Introduction

CAS NO.: 2411681-87-1

Product purity: ≥95%

Molecular formula: C28H38N2O11

Molecular weight: 578.61

Product Usage: Applied to medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

Basic Information

Item Description
Full Name Thalidomide-O-PEG4-t-butyl ester
CAS Number 2411681-87-1
Molecular Formula C28H38N2O11
Molecular Weight 578.6
Purity ≥95% to ≥98%
Appearance White to off-white solid or powder
Solubility Soluble in DMSO, DMF, DCM, and water
Storage Conditions -20°C, dry, protected from light

Detailed Information

Item Description
Structure Consists of a Thalidomide core, a PEG chain with four ethylene oxide units, and a t-butyl ester group
Reactivity The t-butyl ester group can be hydrolyzed to form a carboxylic acid, making it suitable for further conjugation with amines or other nucleophiles
Applications – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers.
Advantages – Combines the properties of Thalidomide, PEG, and a reactive t-butyl ester group.<br>- High biocompatibility and versatility in bioconjugation.

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