
Thalidomide-O-PEG4-NH2
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Category:Biomedicine MOQ:100KG Shipped directly from China
Introduction
CAS NO.: 2401832-00-4
Product purity: ≥95%
Molecular formula: C23H31N3O9
Molecular weight: 493.51
Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.
Basic Information
Item | Description |
---|---|
Full Name | Thalidomide-O-PEG4-Amine |
CAS Number | 2401832-00-4 |
Molecular Formula | C21H27N3O8 |
Molecular Weight | 452.45 |
Purity | ≥95% |
Appearance | White to off-white solid or powder |
Solubility | Soluble in water, DMSO, DMF, and DCM |
Storage Conditions | -20°C, dry, protected from light |
Detailed Information
Item | Description |
---|---|
Structure | Thalidomide core linked to a PEG chain with four ethylene oxide units and an amino group at the end |
Reactivity | The amino group can react with carboxyl groups to form amide bonds or with aldehydes to form Schiff bases |
Applications | – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers. |
Advantages | – Combines the properties of Thalidomide, PEG, and a reactive amino group.<br>- High biocompatibility and versatility in bioconjugation. |
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