Thalidomide-O-PEG4-NH2

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Category:Biomedicine   MOQ:100KG  Shipped directly from China

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Introduction

CAS NO.: 2401832-00-4

Product purity: ≥95%

Molecular formula: C23H31N3O9

Molecular weight: 493.51

Product Usage: Used in medical research, drug release, nanotechnology and new material research, cell culture. As well as in ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

Basic Information

Item Description
Full Name Thalidomide-O-PEG4-Amine
CAS Number 2401832-00-4
Molecular Formula C21H27N3O8
Molecular Weight 452.45
Purity ≥95%
Appearance White to off-white solid or powder
Solubility Soluble in water, DMSO, DMF, and DCM
Storage Conditions -20°C, dry, protected from light

Detailed Information

Item Description
Structure Thalidomide core linked to a PEG chain with four ethylene oxide units and an amino group at the end
Reactivity The amino group can react with carboxyl groups to form amide bonds or with aldehydes to form Schiff bases
Applications – PROTAC Technology: Used as a linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.<br>- Medical Research: Applied in drug release, nanotechnology, and cell culture.<br>- Material Science: Used in the synthesis of functional coatings and polymers.
Advantages – Combines the properties of Thalidomide, PEG, and a reactive amino group.<br>- High biocompatibility and versatility in bioconjugation.

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