Tetraphenylphosphonium chloride

Pharmaceutical Materials 2025-03-02

CAS Number: 2600-51-1.

Molecular Formula: C24H20ClP.

Molecular Weight: 362.84 g/mol.

Appearance: White crystalline powder.

Usage: It is widely used as a phase transfer catalyst and an ion-pairing agent in organic synthesis.

 

Attribute Details
Chemical Name Tetraphenylphosphonium chloride
CAS Number 2001-45-8
Formula C24H20ClP
Molecular Weight 374.84 g/mol
Synonyms Tetraphenylphosphonium chloride, Tetraphenylchlorophosphine, Tetraphenylphosphonium Chloride (TPPCl), Tetraphenylphosphonium salt, Chloride of tetraphenylphosphonium
Appearance White to grayish-white crystalline solid
Melting Point 272-275°C
Solubility Soluble in organic solvents such as toluene, benzene, and chloroform; slightly soluble in water
Chemical Structure Consists of four phenyl groups attached to a central phosphorus atom, with a chloride ion as the counterion
Applications Used as a pharmaceutical intermediate, a cation in studies of membrane transport, and a reagent in organic synthesis
Stability Stable under normal conditions; however, it is hygroscopic and should be stored in a dry environment
Hazards May be harmful if ingested or inhaled; may irritate skin and eyes; handle with appropriate precautions
Storage Conditions Store in a cool, dry place, away from direct sunlight and incompatible materials; keep container tightly closed

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