Tetramethylthiourea
Pharmaceutical Materials 2025-03-02
CAS Number: 2782-91-4
Molecular Formula: C5H12N2S.
Molecular Weight: 132.23 g/mol.
Appearance: White or yellowish crystalline solid.
Usage: It is used as a promoter for acrylate adhesives, a non-polluting vulcanizing agent for chloroprene rubber, and an intermediate for organic pigments.
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
| Property | Details |
|---|---|
| Molecular Formula | C5H12N2S |
| Molecular Weight | 132.23 g/mol |
| CAS Number | 632-22-4 |
| Appearance | White to off-white crystalline solid or powder |
| Purity | Typically ≥98% |
| Melting Point | 176-178 °C |
| Boiling Point | Decomposes before boiling |
| Density | 1.08 g/cm³ |
| Solubility | Soluble in water, ethanol, and DMSO; slightly soluble in ether |
| Applications | Organic synthesis, pharmaceuticals, and agrochemicals |
| Safety Considerations | Handle with care; avoid contact with skin and eyes; store in a cool, dry place away from heat and open flames |
| Suppliers | Available from various chemical suppliers globally |
Applications
Tetramethylthiourea is a versatile compound widely used in organic synthesis, pharmaceuticals, and agrochemicals. Its unique structure, featuring a thiourea group with four methyl substituents, provides distinct reactivity and physical properties, making it a valuable intermediate in the synthesis of various chemicals.
In organic synthesis, Tetramethylthiourea is utilized as a sulfur transfer reagent, a catalyst, or a building block for the synthesis of complex molecules. Its ability to form stable complexes with metal ions also makes it useful in coordination chemistry.
In pharmaceuticals, this compound is employed in the development of drugs with diverse biological activities. The thiourea group can be functionalized to introduce various chemical groups, modulating the pharmacological activity of drug molecules.
In agrochemicals, Tetramethylthiourea finds applications in the synthesis of herbicides and pesticides, offering improved potency and environmental safety. Its solubility in water and organic solvents facilitates its use in various synthetic methodologies, while its stability under appropriate storage conditions ensures its reliability in research and industrial applications.
