Tetramethylguanidine CAS Number: 80-70-6
Pharmaceutical Materials 2025-03-02
CAS Number: 80-70-6
Molecular Formula: C5H13N3
Molecular Weight: 115.177 g/mol
Appearance: Colorless transparent liquid
Melting Point: -30°C Boiling Point: 160-162°C
Density: 0.918 g/cm³ Usage: Used as a strong organic base catalyst in industrial applications.
Tetramethylguanidine, with the CAS number 80-70-6, is an organic compound categorized as a strong organic base. It exists as a colorless to slightly yellow oily liquid with a mild ammoniacal odor. Tetramethylguanidine is widely used in the pharmaceutical industry as a catalyst and co-solvent in the production of cephalosporin antibiotics. Additionally, it serves as a catalyst for polyurethane foam and as a leveling agent for nylon, wool, and other proteins to enhance durability. Due to its corrosive and flammable nature, proper handling and storage are crucial to ensure safety.
| Property | Value |
|---|---|
| Chemical Name | Tetramethylguanidine |
| CAS Number | 80-70-6 |
| Molecular Formula | C5H13N3 |
| Molecular Weight | 115.18 g/mol |
| Appearance | Colorless to slightly yellow oily liquid |
| Density | 0.918 g/mL at 20 °C |
| Melting Point | ≤ -30 °C |
| Boiling Point | 160-162 °C |
| Flash Point | 65 °C |
| Refractive Index | 1.4962 |
| Solubility | Soluble in water, toluene, acetone, and acetyl |
| Stability | Stable; may hydrolyze in alkaline aqueous solution to tetramethylurea |
| Hazard Class | Corrosive liquid, flammable |
| UN Number | UN 2920 |
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