Active Pharmaceutical Ingredients

CAS NO.856867-55-5

Name	Tedizolid phosphate
Synonyms	Tedizolid phosphate Tedizolid Phosphate Tedizolid phosphate impurity A -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate (R) -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone (R) -3- (4- (2- (2- methyl-tetrazol-5-yl) pyridin-5-yl) -3-fluorophenyl) -5-hydroxymethyl-oxazolidin-2-one phosphate (R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogenphosphate (R)-(3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate [(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
CAS	856867-55-5
EINECS	1592732-453-0

Molecular Formula	C17H16FN6O6P
Molar Mass	450.32
Density	1.75±0.1 g/cm3(Predicted)
Melting Point	>235°C (dec.)
Boling Point	725.6±70.0 °C(Predicted)
Solubility	DMSO: ≥ 36 mg/mL
Appearance	Solid
Color	White to Off-White
pKa	1.81±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Stability	Hygroscopic
Use	This product is for scientific research only and shall not be used for other purposes.
In vitro study	Tedizolid (TR-700) is the active part of the prodrug tedizolid phosphate (TR-701) and has activity against Gram-positive bacteria, including methicillin-resistant S. Aureus. Tedizolid is more than 4 times more potent in vitro to antagonize PRSP than linezolid.
In vivo study	Tedizolid has good permeability of lung epithelial mucus layer. Tedizolid phosphate is effective in antagonizing systemic infections in vivo by oral route or intravenous administration. Oral Tedizolid phosphate also effectively antagonized Pneumonia of the induction by the PSSP strain.

Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.

If you're ready to take the next step, Leave your message below and we’ll reply soon. 20+ years of chemical manufacturing & export experience, a partner you can trust.