Temocapril HCl

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Category:Active Pharmaceutical Ingredients   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

Catalog ID80018533

CAS NO.110221-44-8

Purity 98%

MDL NumberMFCD00933433

Molecular FormulaC23H28N2O5S2.HCl

Molecular Weight513.076

Category Details
Chemical Properties Molecular formula: C23H29ClN2O5S2<br> Molecular weight: 528.00
Physical Properties Appearance: White crystalline powder<br> Melting point: 104–106°C or 140–145°C (lit.)
Mechanism of Action Prodrug of temocaprilat, an ACE inhibitor. It inhibits the renin-angiotensin system, causing vasodilation and mild natriuresis without affecting heart rate and contractility.
Therapeutic Uses Indicated for hypertension, congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
Pharmacokinetics Rapidly absorbed in the gastrointestinal tract and converted into the active metabolite temocaprilat. Eliminated primarily through the liver and kidneys.
Half-Life 13.1 hours in patients with normal liver function
Storage Conditions Store in a cool, dry place, protected from light and moisture.
Synonyms Temocapril hydrochloride, CS-622, Acecol

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