Telmisartan
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80021440
CAS NO.144701-48-4
Purity 97%
MDL NumberMFCD00918125
Molecular Formula C33H30N4O2
Molecular Weight 514.6169
Melting point: 265~277°C
| Item | Information |
|---|---|
| Mechanism of Action | Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the angiotensin II type 1 (AT1) receptor, reducing blood pressure by inhibiting the effects of angiotensin II. |
| Indications | – Treatment of hypertension (high blood pressure) to reduce the risk of stroke, heart attack, or death from heart problems.<br>- Used in patients with diabetes to reduce the risk of cardiovascular events. |
| Dosage Forms | Oral tablets (20 mg, 40 mg, 80 mg) . |
| Common Dosage | – Initial dose: 40 mg once daily, which may be increased to 80 mg once daily based on blood pressure response.<br>- Can be taken with or without food. |
| Common Side Effects | – Headache, dizziness, fatigue.<br>- Back pain, sinus swelling, diarrhea.<br>- Nasal congestion, cough, upper respiratory infection. |
| Serious Side Effects | – Hypotension (low blood pressure), especially in patients with low blood volume.<br>- Hyperkalemia (high potassium levels), which can be life-threatening.<br>- Kidney damage, indicated by reduced urine output or swelling in the legs.<br>- Severe allergic reactions, including swelling of the face or throat. |
| Contraindications | – Pregnancy (especially in the second and third trimesters) due to the risk of fetal harm.<br>- Concurrent use with aliskiren in patients with diabetes or kidney disease. |
| Special Precautions | – Regular monitoring of blood pressure and potassium levels.<br>- Caution in patients with liver or kidney disease.<br>- Avoid alcohol, as it may increase the risk of hypotension. |
| Storage Conditions | Store at room temperature (68-77°F or 20-25°C), protected from moisture. |
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