Tedizolamide BASE Cas：856866-72-3
Pharmaceutical Materials 2025-03-02
Tedizolamide BASE (CAS No. 856866-72-3) is a compound with the molecular formula C17H15FN6O3 and a molecular weight of 370.34 g/mol. It is primarily utilized as an antibacterial drug, particularly for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by sensitive Gram-positive bacteria. The compound’s structure features a fluoro group, a methyl group, a tetrazole ring, and a pyridyl group, which may confer unique chemical properties and reactivity.
As an antibacterial drug, it may interact with bacterial ribosomes to inhibit protein synthesis, thereby exerting its therapeutic effect. Although direct pharmacological data on this compound are currently limited, its role in the treatment of ABSSSI suggests that it may possess antibacterial activity. Research on this compound in the fields of chemical synthesis and drug discovery continues, highlighting its potential applications in the pharmaceutical industry.
| Property | Details |
|---|---|
| CAS Number | 856866-72-3 |
| Molecular Formula | C17H15FN6O3 |
| Molecular Weight | 370.34 g/mol |
| Appearance | White or off-white crystalline powder |
| Purity | Not specified, but commonly available in high purity for research and pharmaceutical use |
| Application | Antibacterial drug, particularly for the treatment of acute bacterial skin and skin structure infections (ABSSSI) |
| Structure Features | Fluoro group, methyl group, tetrazole ring, pyridyl group |
| Synthesis | Involves multi-step organic reactions, such as coupling reactions and substitution reactions. Specific synthesis steps not detailed but typical for such compounds |
| Pharmacological Activity | Interacts with bacterial ribosomes to inhibit protein synthesis, exerting antibacterial activity |
| Research Status | Studied in chemical synthesis and drug discovery, with potential applications in the pharmaceutical industry as an impurity control in pharmaceutical analysis |
| Physical Properties | Density: 1.57 g/cm³, Boiling Point: 614.5±65.0°C, Melting Point: 201°C, Solubility: Soluble in DMSO, insoluble in water, slightly soluble in DMF and THF |
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