Tauroursodeoxycholic acid dihydrate
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80020402
CAS NO.14605-22-2
Purity 99+%
MDL NumberMFCD00069496
Molecular Formula C26H45NO6S.2H2O
Molecular Weight 499.71 (Anhydrous)
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₂₆H₄₉NO₈S<br>- Molecular Weight: 535.73 g/mol |
| Physical Properties | – Appearance: White to off-white powder<br>- Melting Point: 173-175°C |
| Mechanism of Action | – Acts as an endoplasmic reticulum (ER) stress inhibitor.<br>- Reduces expression of apoptosis molecules such as caspase-3 and caspase-12.<br>- Inhibits ERK phosphorylation. |
| Biological Activities | – Protects cells from ER stress-induced apoptosis.<br>- Enhances liver function and prevents hepatocellular carcinoma.<br>- Promotes vascular formation and improves cell survival in ischemic models. |
| Applications | – Research: Used in studies related to ER stress, apoptosis, and metabolic disorders.<br>- Clinical Trials: Investigated for treating conditions such as amyotrophic lateral sclerosis (ALS) and progressive multiple sclerosis. |
| Storage Conditions | – Powder: -20°C for up to 3 years.<br>- In solvent: -80°C for up to 6 months. |
| Solubility | – Soluble in DMSO (≥80 mg/mL).<br>- Soluble in ethanol (up to 20 mg/mL with heating). |
| Synonyms | – TUDCA dihydrate.<br>- UR 906 dihydrate.<br>- Taurolite dihydrate. |
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