AHU-377 CAS No.:149709-62-6

AHU-377, chemically known as Sacubitril, is a potent neprilysin (NEP) inhibitor with an IC50 value of 5 nM. It serves as a prodrug in the angiotensin receptor-neprilysin inhibitor (ARNI) LCZ696, where it is combined with valsartan (an angiotensin II receptor blocker) in a 1:1 molar ratio. AHU-377 i…