Sumatriptan succinate CAS NO.103628-48-4
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Category：Active Pharmaceutical Ingredients MOQ:100KG Shipped directly from China
Introduction
Catalog ID80016987
CAS NO.103628-48-4
Purity 98+%
MDL NumberMFCD00902856
EINEC Molecular Formula C14H21N3O2S.C4H6O4
Molecular Weight 413.492
Zoledronic Acid
| Aspect | Details |
|---|---|
| Chemical Structure | – Molecular Formula: C₅H₁₀N₂O₇P₂<br>- Molecular Weight: 272.09 |
| Mechanism of Action | – Inhibits farnesyl pyrophosphate synthase (FPPS), reducing bone resorption by osteoclasts. |
| Clinical Uses | – Treats osteoporosis, Paget’s disease, and high calcium levels due to cancer.<br>- Prevents bone complications in multiple myeloma and metastatic bone disease. |
| Dosage Forms | – Injectable solution. |
| Side Effects | – Common: Flu-like symptoms, headache, bone pain.<br>- Serious: Osteonecrosis of the jaw, atypical femur fractures, kidney problems. |
| Special Precautions | – Monitor renal function and calcium levels.<br>- Use with caution in patients with severe renal impairment. |
| Regulatory Status | – Approved in the US, Europe, and Japan. |
Sumatriptan Succinate
| Aspect | Details |
|---|---|
| Chemical Structure | – Molecular Formula: C₁₈H₂₇N₃O₆S<br>- Molecular Weight: 419.5 |
| Mechanism of Action | – Agonist of 5-HT₁B/₁D receptors, leading to cranial vessel constriction and reduced release of pro-inflammatory neuropeptides. |
| Clinical Uses | – Treats acute migraine and cluster headaches. |
| Dosage Forms | – Tablets, nasal sprays, subcutaneous injections. |
| Side Effects | – Common: Dizziness, somnolence, paresthesia.<br>- Serious: Hypersensitivity reactions, serotonin syndrome. |
| Special Precautions | – Use with caution in patients with ischemic heart disease or uncontrolled hypertension. |
| Regulatory Status | – Approved in the US, Canada, and Australia |
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