Sultamicillin
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80019626
CAS NO.76497-13-7
Purity 96%
MDL NumberMFCD00864948
Molecular Formula C25H30N4O9S2
Molecular Weight 594.66
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₂₅H₃₀N₄O₉S₂<br>- Molecular Weight: 614.62 g/mol |
| Mechanism of Action | – Sultamicillin is a co-drug combining ampicillin and sulbactam. Ampicillin inhibits bacterial cell wall synthesis, while sulbactam irreversibly inhibits beta-lactamases, extending ampicillin’s spectrum to include beta-lactamase-producing strains. |
| Clinical Uses | – Respiratory Tract Infections: Pharyngitis, tonsillitis, sinusitis, otitis media.<br>- Urinary Tract Infections: Pyelonephritis, cystitis.<br>- Skin and Soft Tissue Infections: Furuncles, carbuncles, cellulitis.<br>- Gynecological Infections: Infections caused by beta-lactamase-producing strains.<br>- Gastrointestinal Infections: Part of multidrug therapy for H. pylori infections. |
| Pharmacokinetics | – Sultamicillin improves the absorption of ampicillin and sulbactam compared to separate administration.<br>- Reduces the incidence of gastrointestinal side effects like diarrhea. |
| Adverse Effects | – Generally mild and transient, though severe cases may require discontinuation.<br>- Higher incidence of diarrhea compared to some other antibiotics. |
| Storage Conditions | Store in a cool, dry place, protected from moisture. |
| Synonyms | – Unacid<br>- Combisid |
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