Sodium thioctate
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80021580
CAS NO.2319-84-8
Purity 98%
MDL NumberMFCD00243000
Molecular FormulaC8H13O2S2.Na
Molecular Weight228.3074
Melting point: 250~253°C
| Item | Information |
|---|---|
| Chemical Name | Sodium Thioctate (Sodium α-Lipoate) |
| CAS Number | 2319-84-8 |
| Molecular Formula | C₈H₁₃NaO₂S₂ |
| Molecular Weight | 228.31 |
| Structure | 5-(1,2-Dithiolan-3-yl)pentanoate |
| Physical Properties | – Boiling Point: 362.5°C at 760 mmHg<br>- Flash Point: 173°C |
| Solubility | Soluble in water |
| Uses | – Antioxidant and cofactor for mitochondrial enzymes.<br>- Inhibits NF-κB-dependent HIV-1 LTR activation.<br>- Used in the treatment of diabetic neuropathy and other conditions related to oxidative stress. |
| Safety | – Generally considered safe at doses up to 2400 mg/day.<br>- Side effects may include nausea and gastrointestinal discomfort.<br>- Rarely associated with insulin autoimmune syndrome (IAS) in genetically susceptible individuals. |
| Storage Conditions | Store in a cool, dry place |
| Additional Notes | – Also known as α-lipoic acid sodium salt.<br>- Rapid absorption with peak plasma levels reached within 0.5-1 hour.<br>- Best taken on an empty stomach |
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