Sodium cromoylycate CAS NO.15826-37-6
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80017136
CAS NO.15826-37-6
Purity 98%
MDL NumberMFCD00057744
EINEC239-926-7
Molecular FormulaC23H14O11Na2
Molecular Weight 512.3302
| Aspect | Details |
|---|---|
| Mechanism of Action | Sodium cromoglycate is a mast cell stabilizer that prevents the release of inflammatory mediators such as histamine and leukotrienes. It inhibits mast cell degranulation, which is responsible for allergic symptoms and bronchoconstriction. Unlike antihistamines, it acts by stabilizing mast cells rather than blocking histamine receptors. |
| Clinical Uses | It is used for the prevention and treatment of allergic conditions, including asthma, allergic rhinitis, hay fever, and allergic conjunctivitis. It is also used in the management of mastocytosis. |
| Pharmacokinetics | Sodium cromoglycate is poorly absorbed when administered orally or via the eyes. Less than 0.07% of the administered dose is absorbed systemically. It has a half-life of 80–90 minutes and is primarily excreted unchanged in feces. |
| Dosage Forms | Available as eye drops, nasal sprays, and inhalers. Typical dosing for eye drops is 1–2 drops into each eye 4 times daily. |
| Side Effects | Common side effects include transient stinging or burning sensation after application, throat irritation, cough, and bad taste. Rare side effects may include bronchospasm, laryngeal edema, and anaphylaxis. |
| Storage Conditions | Store at room temperature (less than 30°C) before opening. After opening, store below 25°C and discard any unused solution 4 weeks after first opening. |
| Special Precautions | Use with caution in patients with known hypersensitivity to the drug or its components. Sudden withdrawal may cause allergic symptoms. |
| Handling and Disposal | No special requirements for disposal. Store in properly labeled containers and protect from direct sunlight |
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