Sinomenine HCl
Active Pharmaceutical Ingredients 2025-03-03
Catalog ID80020694
CAS NO.6080-33-7
Purity 98%
MDL NumberMFCD01714307
Molecular FormulaC19H23NO4.HCl
Molecular Weight365.8512
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₉H₂₄ClNO₄ <br>- Molecular Weight: 365.85 <br>- CAS Number: 6080-33-7 |
| Physical Properties | – Appearance: White to off-white powder <br>- Melting Point: 231.0 to 235.0 °C <br>- Solubility: Soluble in water (20 mg/mL), methanol, ethanol, DMSO |
| Mechanism of Action | – Blocks NF-κB activation <br>- Activates μ-opioid receptors |
| Biological Activities | – Antinociceptive effects in animal models <br>- Reduces mechanical and cold allodynia without motor deficits or sedation at 40 mg/kg <br>- Inhibits cell migration and wound healing in vitro |
| Applications | – Treatment of rheumatoid arthritis <br>- Potential use in pain management and anti-inflammatory therapy |
| Storage Conditions | – Store at 4°C, sealed, away from moisture <br>- In solvent: -80°C for 1 year; -20°C for 6 months |
| Safety Information | – LD₅₀ orally in mice: 580 mg/kg <br>- RTECS Number: QD2163000 <br>- WGK Germany: 3 |
Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
