Sinomenine HCl
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80020694
CAS NO.6080-33-7
Purity 98%
MDL NumberMFCD01714307
Molecular FormulaC19H23NO4.HCl
Molecular Weight365.8512
| Category | Information |
|---|---|
| Chemical Properties | – Molecular Formula: C₁₉H₂₄ClNO₄ <br>- Molecular Weight: 365.85 <br>- CAS Number: 6080-33-7 |
| Physical Properties | – Appearance: White to off-white powder <br>- Melting Point: 231.0 to 235.0 °C <br>- Solubility: Soluble in water (20 mg/mL), methanol, ethanol, DMSO |
| Mechanism of Action | – Blocks NF-κB activation <br>- Activates μ-opioid receptors |
| Biological Activities | – Antinociceptive effects in animal models <br>- Reduces mechanical and cold allodynia without motor deficits or sedation at 40 mg/kg <br>- Inhibits cell migration and wound healing in vitro |
| Applications | – Treatment of rheumatoid arthritis <br>- Potential use in pain management and anti-inflammatory therapy |
| Storage Conditions | – Store at 4°C, sealed, away from moisture <br>- In solvent: -80°C for 1 year; -20°C for 6 months |
| Safety Information | – LD₅₀ orally in mice: 580 mg/kg <br>- RTECS Number: QD2163000 <br>- WGK Germany: 3 |
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