Salbutamol sulfate CAS NO.51022-70-9

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Category:Active Pharmaceutical Ingredients   Own Brand:MT  /MOQ:100KG  /From China/  B2B only.

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Introduction

Catalog ID80017807

CAS NO.51022-70-9

Purity 99%

MDL NumberMFCD00055200

EINEC256-916-8

Molecular formula (C13H21NO3)2.H2SO 4

Molecular weight 576.7

Melting point: 180°C

Flash point: >250°C

Aspect Details
Mechanism of Action Salbutamol sulfate (also known as albuterol sulfate) is a selective β2-adrenergic receptor agonist. It acts by stimulating β2-adrenergic receptors in the lungs, leading to relaxation of bronchial smooth muscles and bronchodilation. It also inhibits the release of bronchoconstricting agents from mast cells and enhances mucociliary clearance.
Pharmacokinetics Salbutamol is rapidly absorbed after inhalation and acts locally on the bronchial smooth muscles. It is metabolized in the liver to an inactive sulfate ester (salbutamol 4′-O-sulfate) and excreted primarily through urine. The elimination half-life is approximately 3.8 to 5 hours.
Storage Conditions Salbutamol sulfate should be stored in a refrigerator at 2 to 8°C.
Special Considerations Use with caution in patients with cardiovascular diseases, as salbutamol may cause cardiovascular effects such as tremors, hypokalemia, and arrhythmias. Overdose can lead to severe toxicity, including lactic acidosis and metabolic disturbances

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