(S)-(+)-3-Hydroxytetrahydrofuran
Category：Pharmaceutical Materials
Introduction
S-3-Hydroxytetrahydrofuran is an organic compound.
S-3-hydroxytetrahydrofuran is a colorless liquid with a unique odor. It is a solvent with strong polarity and hydrophilicity, and can dissolve many organic compounds and inorganic salts.
S-3-hydroxytetrahydrofuran has various uses in the chemical industry. It is an excellent solvent that can be used in organic synthesis reactions, such as hydrogenation reactions, condensation reactions, etc.
A common method for preparing S-3-hydroxytetrahydrofuran is through a reduction reaction. Specifically, furan can be oxidized to generate hydroxyfuran, which can then undergo a reduction reaction to obtain S-3-hydroxytetrahydrofuran.
This compound is irritating to the eyes and skin, and should be avoided from direct contact when used. It should be operated in a well ventilated area to avoid inhaling its vapors. During storage, keep away from high temperatures and open flames.
| Name | S-3-hydroxytetrahydrofuran |
| Synonyms | (3S)-oxolan-3-ol Afatinib intermediate B (S)-tetrahydrofuran-3-ol (S)-TETRAHYDROFURAN-3-OL (3S)-tetrahydrofuran-3-ol S-3-hydroxytetrahydrofuran (S)-(+)-TETRAHYDRO-3-FURANOL (S)-3-Hydroxytetrahydrofuran S(+)-3-hydroxyTetrahydrofuran (S)-(+)-3-Hydroxytetrahydrofuran Thiophene-3-ol,tetrahydro-, (S)- Thiophene-3-ol,tetrahydro-, (3S)- (S)-(+)-3-HYDROXY TETAHYDRO FURAN Hydroxytetrahydrofuran, (S)-(+)-3- (S)-(-)-3-HYDROXY TETRAHYDRO FURAN (2S)-1,4-Epoxy-2-hydroxybutane, (3S)-Tetrahydrofuran-3-ol, (3S)-Oxolan-3-ol |
| CAS | 86087-23-2 79107-75-8 |
| EINECS | 1308068-626-2 |
| InChI | InChI=1/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m0/s1 |
| InChIKey | XDPCNPCKDGQBAN-BYPYZUCNSA-N |
| Molecular Formula | C4H8O2 |
| Molar Mass | 88.11 |
| Density | 1.103 g/mL at 25 °C (lit.) |
| Boling Point | 80 °C/15 mmHg (lit.) |
| Specific Rotation(α) | 18.5 º (c=2 MeOH) |
| Flash Point | 175°F |
| Water Solubility | soluble |
| Solubility | Chloroform, Methanol (Slightly) |
| Vapor Presure | 47Pa at 25℃ |
| Appearance | Liquid |
| Specific Gravity | 1.11 |
| Color | Clear colorless to pale yellow |
| BRN | 4652609 |
| pKa | 14.49±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Refractive Index | n20/D 1.45(lit.) |
| Physical and Chemical Properties | Appearance colorless transparent liquid boiling range ℃(15mmHg) 79-80 |
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