S-(+)-2-Amino-1-propanol
Pharmaceutical Materials 2025-03-02
CAS Number: 2749-11-3
Molecular Formula: C3H9NO
Molecular Weight: 75.11 g/mol
Appearance: Colorless or light yellow transparent liquid
Boiling Point: 173-176°C
Density: 0.965 g/mL
Usage: Used as an intermediate in organic synthesis and as an emulsifier.
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| Attribute | Information |
|---|---|
| Chemical Name | S-(+)-2-Amino-1-propanol |
| CAS Number | 156-87-6 |
| Synonyms | (S)-1-Aminopropan-2-ol; (S)-2-Aminopropanol; (S)-(-)-2-Aminopropan-1-ol |
| Molecular Formula | C3H9NO |
| Molecular Weight | 75.11 g/mol |
| Appearance | Clear, colorless to slightly yellow liquid |
| Melting Point | -19 °C |
| Boiling Point | 157-159 °C |
| Density | 0.965 g/mL at 25 °C |
| Refractive Index | 1.443-1.445 |
| Solubility | Miscible with water, alcohol, and ether |
| Chirality | S-(+)-configuration |
| Chemical Structure | Contains a primary amino group and a secondary alcohol group on adjacent carbon atoms |
| Physical Properties | Has a mild, amine-like odor and is slightly hygroscopic |
| Uses | Used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a chiral ligand in asymmetric catalysis. |
| Synthesis Methods | Prepared by the reduction of (S)-(+)-2-aminopropionic acid or its esters, or by the asymmetric hydrogenation of the corresponding ketone. |
| Health Effects | May cause irritation to skin, eyes, and respiratory tract. Ingestion may be harmful. |
| Environmental Considerations | Handle and dispose of S-(+)-2-Amino-1-propanol according to local environmental regulations. |
| Safety Precautions | Wear appropriate protective clothing and eye protection. Store in a cool, dry place, away from heat, sparks, and open flames. Keep away from oxidizing agents. |
