(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol Cas：877397-65-4
Pharmaceutical Materials 2025-03-02
(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol, with the CAS number 877397-65-4, is a chiral alcohol compound that exhibits a wide range of applications in the field of organic synthesis and pharmaceutical chemistry. This compound features a 2,6-dichloro-3-fluorophenyl group substituted at the 1-position of an ethanol molecule.
Due to its chiral nature, (S)-1-(2,6-dichloro-3-fluorophenyl)ethanol offers unique reactivity and selectivity, making it a valuable intermediate in the synthesis of various chiral drugs and bioactive compounds. It is typically a white or off-white solid with high purity and stability. This compound has been identified as an intermediate in the synthesis of drugs such as crizotinib, a tyrosine kinase inhibitor used in the treatment of cancer.
| Product Information | Details |
|---|---|
| Compound Name | (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol |
| CAS Number | 877397-65-4 |
| Molecular Formula | C8H7Cl2FO |
| Molecular Weight | 209.04 g/mol |
| Physical State | White or off-white solid |
| Purity | ≥98% |
| Melting Point | 42-46 °C |
| Boiling Point | 261.329 °C at 760 mmHg |
| Density | 1.407 g/cm³ |
| Refractive Index | 1.547 |
| Flash Point | 111.848 °C |
| PSA | 20.23000 Ų |
| Usage | Pharmaceutical intermediate, organic synthesis intermediate |
| Storage Conditions | Store in a cool, dry place, away from light and moisture |
| Stability | Stable under recommended storage conditions |
| Hazard Information | Potential skin and eye irritant, handle with care |
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