(S)-1-(2-Iodo-5-fluorophenyl)ethanol Cas：1454847-96-1
Pharmaceutical Materials 2025-03-02
(S)-1-(2-Iodo-5-fluorophenyl)ethanol, with the CAS number 1454847-96-1, is a key chiral intermediate in the synthesis of pharmaceutical compounds. This compound features a fluorinated and iodinated aromatic ring attached to an ethanol group, conferring unique stereochemical and physicochemical properties.
It serves as an important building block in the synthesis of drugs such as Lorlatinib, a third-generation anaplastic lymphoma kinase (ALK) inhibitor used in the treatment of non-small cell lung cancer. The high purity and chirality of (S)-1-(2-iodo-5-fluorophenyl)ethanol make it a crucial reagent in the pharmaceutical industry.
| Product Properties | Details |
|---|---|
| CAS Number | 1454847-96-1 |
| Chemical Name | (S)-1-(2-Iodo-5-fluorophenyl)ethanol |
| Synonyms | (S)-1-(5-fluoro-2-iodophenyl)ethan-1-ol |
| Molecular Formula | C8H8FIO |
| Molecular Weight | 266.05 g/mol |
| Appearance | White to off-white powder |
| Purity | ≥99% |
| Melting Point | N/A |
| Boiling Point | 275.7 ± 30.0 °C (predicted) |
| Density | 1.812 ± 0.06 g/cm³ (predicted) |
| Usage | Pharmaceutical intermediate, particularly in the synthesis of Lorlatinib |
,Disclaimer: The above content is for reference and communication only among industry insiders, and does not guarantee its accuracy or completeness. According to relevant laws and regulations and the regulations of this website, units or individuals who purchase related items should obtain valid qualifications and qualification conditions.
