Rutaecarpine
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Category：Active Pharmaceutical Ingredients Own Brand：MT /MOQ:100KG /From China/ B2B only.
Introduction
Catalog ID80019297
CAS NO.84-26-4
Purity 98%
MDL NumberMFCD00210551
Molecular Formula C18H13N3O
Molecular Weight 287.32
Melting point: 260~266°C
| Category | Details |
|---|---|
| Chemical Properties | Rutaecarpine is an indolopyridoquinazolinone alkaloid with the molecular formula C18H13N3O and a molecular weight of 287.31. It is a solid compound that crystallizes from boiling ethanol as colorless or pale yellow needles. |
| Physical Properties | Melting point: 209°C at 760 mm Hg. |
| Solubility | Very slightly soluble in water. |
| Pharmacological Effects | Rutaecarpine has a wide range of biological activities, including cardiovascular effects such as inotropic and chronotropic actions, vasorelaxant effects, anti-platelet aggregation, and anti-inflammatory properties. It also exhibits diuretic, uterotonic, and anti-obesity effects. |
| Mechanism of Action | Rutaecarpine activates transient receptor potential vanilloid (TRPV1) receptors, which leads to the release of calcitonin gene-related peptide (CGRP), contributing to its cardiovascular and anti-inflammatory effects. It also inhibits phospholipase C activity, reducing platelet aggregation. |
| Applications | Used in traditional medicine for treating cardiovascular diseases, inflammation, and other conditions. It is also studied for its potential in treating hypertension and thrombosis. |
| Safety and Precautions | Rutaecarpine has significant pharmacological effects and should be used under medical supervision. Its cardiovascular effects require careful consideration in patients with heart conditions. |
| Storage Conditions | Store in a cool, dry place, protected from light and moisture. |
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